Treating Depression


⅔ of people have a successful response to ketamine infusions and ⅓ of patients experience remission

Up to half of all people with depression are not adequately treated by conventional therapies, or cannot tolerate the side effects of antidepressant medications. Many continue to suffer from what is called treatment-resistant depression. Today, depression is the leading cause of disability in the world, underscoring the great need for better treatment options. Scientific studies done at the National Institute of Mental Health and academic centers throughout the world have found that over ⅔ of people have a successful response to ketamine infusions for treatment-resistant depression. A response is generally considered to be a 50% reduction in symptom severity as measured by depression rating scales. About ⅓ of people have complete remission of their depression. Studies also show that ketamine significantly improves suicidal thoughts. People who do respond to treatment with ketamine have rapid relief of their suffering, and often feel significant and long-lasting improvements in mood and well-being within hours to days.

How long the treatment effects last depends on the individual. Clinical experience suggests that the effect of the recommended full course of 6 infusions usually lasts from weeks to months. It has been observed that people with a family history of alcohol abuse actually have much longer lasting effects. This benefit can be sustained by doing a single booster infusion as needed and determined by your individual response. Some people even find that they no longer need to take antidepressants. To solidify the gains you have from your treatment and to ensure long-lasting success, it is important to continue to see your primary physician or mental health care provider.